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Top 10 HIV and Hepatitis Stories of 2011

In our last issue for 2011, HIVandHepatitis.com reviews some the year's major news highlights. HIV prevention garnered the most headlines, with studies showing that antiretroviral therapy (ART) prevents transmission and pre-exposure prophylaxis (PrEP) works -- at least for some people some of the time. On the hepatitis C front, the first new direct-acting antiviral drugs were approved, ushering in a new era of more effective treatment.alt

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Congress Reinstates Federal Funding Ban on Needle Exchange

House Republican legislators added language banning federal funding of needle and syringe exchange programs to key appropriations bills last week, and the Senate let the restrictions stand in the compromise legislation.

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Math Model Suggests PrEP plus ART Would Lower HIV Drug Resistance

An appropriate combination of pre-exposure prophylaxis (PrEP) and antiretroviral therapy (ART) could potentially reduce the prevalence of drug-resistant HIV in resource-limited countries, but the wrong balance could increase resistance and the need for second-line therapy, according to a mathematical model described in the December 7, 2011, Nature Scientific Reports.alt

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Gilead Requests FDA Approval of Truvada for HIV Prevention

Gilead Sciences announced this week that it has submitted a supplemental New Drug Application to the U.S. Food and Drug Administration (FDA) requesting approval of a new indication for Truvada, its tenofovir/emtricitabine combination pill, for HIV pre-exposure prophylaxis (PrEP). If granted, it would be the first antiretroviral to be approved for HIV prevention.alt

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CDC Announces $300 Million in HIV Prevention Funding Grants

The U.S. Centers for Disease Control and Prevention (CDC) last week announced the first round of grant awards to state and local health departments as part of its new "high-impact" HIV prevention initiative. The CDC launched the initiative earlier this year, emphasizing prevention efforts that target the most heavily impacted regions and population groups -- in particular young black gay men -- and are supported by scientific evidence.alt

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